Multicentric Study of Clinicopathological Features of Primary Gastrointestinal Lymphoma of Iran: from 2011 - 2016

Background: Gastrointestinal (GI) tract is the most common site for extranodal lymphoma. The primary GI lymphoma pattern in Iran different from western countries and has been changed during past 40 years. Objectives: This study was done to determine clinical pathological characteristics of Tehran, Hamedan, Mashhad regions Iran. Methods: In this cross-sectional comparative-descriptive study, 200 patients with Hamadan, 2011 2016 were enrolled a consecutive manner, where cases determined. Results: Among patients, 141 (70.5%) subjects male 59 (29.5%) female. mean age at diagnosis 54.3 ± 19.3 Also, 84%, 8.5%, 7.5% patients’ specimens Mashhad, respectively. stomach principal involved location approximately half cases. Diffuse large B-cell (DLBCL), main subtype that observed 64% Treatment 72% combination surgery chemotherapy. 5-year survival assessed 147 rate 68%. Conclusions: Primary seen more younger than 60 years non-specific symptoms. DLBCL MALToma are histologic types, all 68.0%. symptoms showed no specific accordingly, weight loss abdominal pain should be considered differential malignant